Our expertise dedicated to your experiments
Single Cell Isolation
By combining the expertise of our talented team with our versatile cellenONE® platforms, we offer a range of ultra-gentle single cell isolation services with up to 100% single cell accuracy.
Any cell, any sample
Our unique technology allows us to process any cells (mammalian, plant, spore, bacteria) from 0.5 to 80 µm diameter from any sample size (from as little as 1µL). When most single cell isolation technologies require 1000’s of cells, cellenONE can process even the smallest samples with fewer than 100 cells with no cell loss (ideal for rare cells and microbiopsies).
Trust what you see
Prior to isolation, every sample is visually inspected, and its preparation can thus be further tailored if required. More importantly, each and every isolated cell is imaged, and its picture recorded, allowing you to gain unparalleled confidence in your results.
Combined morphology and fluorescent profiling
Cells can be isolated based on morphological features, fluorescence, or a combination of the two with up to four fluorescence markers which allow removal of dead cells or selection of specific sub-populations.
Isolate cells into any substrate such as cellenCHIP, microtiter plate (96, 384, 1536wp), microchips, or onto any surface such as microscope slides or other customized formats that can be specifically set up by our team of experts to suit your needs and applications.
Single Cell Omics
We offer a range of tailored solutions to suit all your single cell omics analyses.
3’ scRNA-Seq services
We offer complete single cell transcriptomic analyses based on our cellenCHIP 384 3’RNA-Seq kits. These tailored services include single cell isolation into cellenCHIP 384, library preparation and quality controls, next generation sequencing (Illumina®) all the way to data analysis, visualisation, and interpretation.
Your sequencing data will be processed through our dedicated analysis pipeline on our local servers to provide in-depth quality control and data visualisation. Custom data analyses to facilitate interpretations are also offered by our team of experienced bioinformaticians.
Full length scRNA-Seq services
We offer full length single cell transcriptomic analyses based on commercial kits. These tailored services include single cell isolation, library preparation and quality controls, next generation sequencing (Illumina®) all the way to data analysis, visualisation, and interpretation.
Other single cell omics services
We are continuously developing and implementing new protocols for single cell omics analyses. If what you are looking for isn’t described here, please contact our team to discuss your specific requirements.
Single Spheroid Isolation
Using our spheroONE technology, we offer a range of services to facilitate cellular aggregates preparation and improve outcomes of your 3D cell assays.
Cellular aggregates sorting and isolation
Automated sorting and isolation of cellular aggregates such as spheroids, organoids and embryos of sizes up to 600 µm into the substrate of your choice (96, 384, 1536wp). Our gentle dispensing technology maintains the integrity and viability of fragile cellular aggregates.
Improved assay quality
spheroONE enables size and morphology sorting together with isolation of user-defined number of spheroids per well, allowing controlled biomass for meaningful and high quality cytological assays (high Z’ score).
Cell Line Development
We offer a range of automated cloning solutions to suit even the most challenging cell line development projects.
High Accuracy and Confidence
Our highly accurate single cell isolation technology ensures that every well will contain one and only one single cell. Each and every isolated cell is imaged, and its picture recorded, allowing you to gain unparalleled confidence in monoclonality, enhancing your results and supporting your application to the relevant regulatory authorities.
Highest clonal outgrowth
Our ultra-gentle single cell isolation technology has been proven to achieve the highest clonal outgrowth in the industry.
Example of applications
Single cell cloning has become a critical step for many applications ranging from monoclonal antibody development, gene editing studies (e.g. CRISPR), stem cell projects (e.g. iPS).
What you can expect from us
Over our young history, we have gained great expertise in processing difficult samples. As scientists we love those challenges: if such samples are important to your pre-clinical studies or R&D activities, don’t hesitate to contact us
What to expect from us?
If you have any cells you want to isolate our application you want to develop, please contact our experts in single cell isolation at [email protected].
From experimental design to data analysis, our multidisciplinary team will work closely with you at every step in order to ensure that the service provided will match your expectations.
By combining our latest technologies (cellenONE® and spheroONE®) with the expertise of our scientific team, we offer you a range of tailored solutions.