Single Cell Omics

Scalable nanoliter volume library preparation of single cells

Single-Cell Omics

Scalable nanoliter volume library preparation of single cells

Most current methods are based on either microfluidics platforms, which do not offer multiple interventions for complex sequencing libraries preparations, or on large volume microplate-based sample preparations that tend to be expensive due to reagent costs.

cellenONE® technology breaks away from these limitations by combining the small volumes found only in microfluidics with the flexibility of a liquid handler to enable scalable nanoliter volume library preparation of single cells.


Miniaturized 3' scRNA-seq

A 3’ scRNA-seq protocol was developed in the cellenCHIP using a range of commercially available reagents. The following steps describe the workflow using cellenCHIP and cellenONE®

Single Cell Transcriptiomics

Open Platform

  • Any single-cell omics approaches (genomics, epigenetics, transcriptomics, proteomics, metabolomics…)
  • Compatible with most commercially available and published protocols
  • Just dispense single cells in any dedicated reagent x consumable

Transcriptiomics Success Story

Marco Marra’s lab and collaborators

(University of British Columbia, BC Cancer Vancouver)

  • First miniaturised Total scRNAseq method (lysis in 5.5 nL!)
  • First stranded Total scRNAseq method
  • First automatized Total scRNAseq method

“We demonstrate that our method […] enabled the profiling of transcript regions beyond only transcript termini, and yielded data rich enough to allow identification of cell types from heterogeneous biological samples”

Haile et al. 2021, Frontiers in Genetics

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cellenONE® is a revolutionary technology with advanced visual processing solutions that provides real-time and high accuracy single cell isolation and dispensing.

proteoCHIP Product Line

Provides scientists with innovative tools to facilitate miniaturized sample preparation of individual cells for single cell proteomics workflows.