cellenONE®
The open platform for single cell isolation and nanoliter dispensing
cellenONE® X1
Image-based single-cell sorting and dispensing in 96, 384 & 1536 well plates or cellenCHIP
cellenONE® F1.4
Multi-fluorescence image-based single-cell sorting and dispensing in 96, 384 & 1536 well plates or cellenCHIP
cellenONE® BSC
Image-based single-cell sorting and dispensing in 96, 384 &1536 well plates or cellenCHIP, integrated under a class II biosafety cabinet
High accuracy single cell isolation and dispensing
cellenONE® is a revolutionary platform based on sciDROP PICO precision dispensing technology and coupled with advanced image processing that provides real-time and high accuracy single cell isolation and dispensing.
Using gentle acoustic waves for droplet generation, cellenONE® preserves outstanding cell viability for all cloning applications and maintains protein expressions for sequencing applications.
Versatile technology for a variety of samples
High-resolution optics allows isolation of any cell type (mammalian cells, bacteria, fungi, archea, plants, etc…) from any sample size.
Working in aspirate/dispense mode allows high recovery of a wide range of samples, from minute cell suspensions containing just a couple of microliters and a few dozen cells to much larger samples containing thousands of cells.
Benefits of cellenONE®
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High accuracy single cell isolation and dispensing
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Gentle on cells, ensuring outstanding cell viability
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Compatible with a wide range of particle sizes (0.5 µm – 80 µm)
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Ideal for rare cell samples (zero dead volume and high recovery)
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High-throughput isolation of hundreds of cells in only a few minutes
Benefits of cellenONE
-
High accuracy single cell isolation and dispensing
-
Gentle on cells, ensuring outstanding cell viability
-
Compatible with a wide range of particle sizes
-
Ideal for rare cell samples (zero dead volume and high recovery)
-
High-throughput isolation of hundreds of cells in only a few minutes
Applications
cellenONE® are low volume, high viability and high accuracy single cell isolation systems for both single cell omics and cell line development applications.
Single Cell Omics
scRNA-seq
scWGS
scMS
scATAC-seq
Cell Line Development
mAb
Stem cells
CRISPR/CAS9
µ-Bio
Cloning
We have worked successfully with a large variety of cell types
CHO, Hybridoma, HEK293T, HeLa, A549, PC3, H1975, HepaRG
From cell line, fresh frozen (FF) and formalin-fixed paraffin-embedded (FFPE) tissue slices
PMMA microbeads from 2 to 30µm diameters
TOYOPEARL®
PS microbeads
PBMC (including B- and T- cell fractions)
Fibroblasts, keratinocytes, melanocytes, cardiomyocytes, HUVEC
Neural Stem Cells
Application notes
SCoPE2-MS using cellenONE®
Unparalleled clonal outgrowth in 96 384 and 1536 MTP
Scaling Whole Genome Sequencing to > 50,000 Single cells using cellenONE®
Product specifications
|
cellenONE® X1 |
cellenONE® F1.4 |
|
| Sorting Technology |
Brightfield images |
Brightfield and/or |
| Dispensing Technology |
sciDROP PICO: 250-600 pL / single drop |
|
| Number of Dispensing Channels |
Up to 2 |
|
| Spottable Area (X x Y) |
252 x 112 mm |
|
| Target Capacity |
2 MTPs or 8 standard glass slides |
|
| Axis System |
X-Y Linear Magnetic Drive, Z Spindle Drive |
|
| Axis Precision |
< 3 µm |
|
| Dimensions with Enclosure (L x W x H) |
650 x 700 x 1590 mm |
|
| Weight |
205 kg |
|
cellenONE® X1
For applications where sorting based on cell morphology is sufficient
cellenONE® F1.4
For applications requiring multichannel fluorescence sorting and imaging
cellenONE® BSC
For applications where full protection of sample, operator, and environment is required
