CELLEN ONE SINGLE CELL DISPENSERS

All-in-one platforms: high-accuracy single cell isolation + high-precision pico- to nanoliter reagent dispensing.

Single cell isolation

Precision liquid dispensing

On-deck temperature control

Brightfield and/or Fluorescence

Image recording of every isolated cell

End-to-end sample preparation workflows

applications

single cell proteomics

Sample preparation is the critical bottleneck in single-cell proteomics. Every handling step risks sample loss and variability.

cellenONE works out of the box with proteoCHIP consumables for end-to-end automated workflows, or integrates into custom label-free and multiplexed LC-MS/MS setups. The proteoCHIP EVO 96 label-free workflow identifies up to 4,000 proteins per single cell. Learn More

SPATIAL PROTEOMICS AT SINGLE-CELL RESOLUTION

Spatial proteomics requires precise, low-loss preparation from defined tissue microregions while preserving spatial context.

cellenONE automates dispensing of tissue-derived samples onto proteoCHIP consumables, processing up to 192 samples in under 3 hours with approximately 2,000 proteins identified per microregion.

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Cell Line Engineering

CRISPR editing, iPSC reprogramming, and vector production workflows demand multi-marker sorting and documented clonality at every step.

cellenONE X1 NEO combines up to four fluorescence channels with image-based single-cell deposition, providing simultaneous multi-parameter detection and verified clonality for regulatory and experimental confidence.’

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Synthetic Biology

Microbial strains engineered to produce DNA, proteins, or metabolites require monoclonal isolation to ensure culture purity and production reliability at scale.

cellenONE isolates individual microbial cells with image-based precision, establishing pure, stable cultures for downstream biomanufacturing. Compatible with bacteria and other microorganisms down to 0.5 µm, it supports strain validation and library generation for synthetic biology workflows.

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About cellenONE

Combining ultra-precise image-based single‑cell isolation with gentle droplet dispensing, the cellenONE single cell dispensers deliver 100% accuracy, exceptional viability, and compatibility with cells sized 0.5–80 µm.

They empower breakthroughs in various cutting-edge applications, such as single cell omics, spatial proteomics, cell engineering and high-throughput bioprocessing. Available in multiple versions to fit diverse application needs, from R&D to GMP environments..

Connect with an Expert

TRUSTED BY LEADING INSTITUTIONS

> 220 cellenONE dispensers globally, pioneering single cell breakthroughs daily

"So, the main advantage that I see from the cellenONE over any other robotic system that we had before is that we can work with a picoliter range volume, so very very small volumes, and this is quite an advantage, in the single cell field, because higher volumes would mean that we have lower concentration of the proteases would mean that we have higher losses of hydrophobic peptides to any raw material of our tubes so, to work in picoliter to nanoliter volumes really enabled us to achieve the numbers that we get."

Dr Manuel Matzinger

Vienna Biocenter, Austria

“With the cellenONE, the isolation is gentle – besides we can do it in a fast way, which is comfortable for the cells to be back on their media. Also we can keep part of the sample in case we need to retrieve it. The rate survival is very good compared to what we were using before with manual and FACS techniques.”

Valeria Fernandez Vallone, PhD

Berlin Institute of Health at Charité, Germany

“cellenONE is easy to manipulate, very easy to operate, and dispensing is fast. I would say, it allows to dispense without too much effort. So, it was easier with good results. Single cell dispensing with cellenONE is accurate, also cuts costs.”

Young Min Oh

GI INNOVATION, South Korea

"First of all, I have to say that I do agree that this (cellenONE) is the best device for single cell proteomics.“

Dr Zilu Ye

University of Copenhagen, Denmark

"I think there is actually a lot of potential for growth, and application for single cell Strand- Seq, and I think cellenONE will play an important role in that. Because the key to the success of this method is is miniaturization, if you want to sequence the DNA in a single cell, If you want to do it the way we do it, with Illumina adaptors, you need to first fragment the DNA and they litigate these adaptors, and that's much more efficient if you can reduce the volume, and that can be done using the kind of platform that cellenONE supports."

Prof. Peter Lansdorp

British Columbia Cancer Research Center, Canada

ONE PLATFORM, DIFFERENT VERSIONS

cellen one X1 NEO

All-in-one platform combining high-accuracy single cell isolation and high-precision pico to nanoliter reagent dispensing

cellen one HT

True walk-away solution for efficient, automated and high throughput monoclonal cell line development

cellen one BSC

Single cell workflows under protection

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